merten @houdinihound is correct, the "issues" referenced on the status page were regarding the DE SMTP block from last week. That's been resolved and we've closed out that issue as of this morning.
The gateway errors on opal5 are due to abusive traffic to a customer site which is overloading the Apache service. We're working with the site operator to resolve that and we'll be rolling out some changes to our Apache/PHP setup in the near future to make this type of issue less likely to occur.